I want to...

Automate Throughput	Lower Run Cost
Decrease Labor Prep Time	Increase Throughput
Improve Quantity/Quality Assessment	Increase Detection Sensitivity

I want to Lower Run Costs

Advanced Analytical offers per sample run costs of 50% to 70% lower than the competition (before factoring in the cost of labor).

NGS fragment analysis is a critical step in the library production process of Next Gen Sequencing preparations. Using chip-based methods for NGS fragment analysis rapidly becomes very expensive for a variety of reasons:

• per sample costs for lab-on-a-chip methods range from $2 to $5 per sample.
• chip-based methods require significant amounts of labor, consisting primarily of pipetting and other chip-handling tasks.
• hidden cost: some labon-chip-systems demand that the chips must be used within five minutes after loading - or be thrown away. If a lab technician is interrupted and distracted soon after loading the chip, then that cost is absorbed by the lab.
• hidden cost: gel shelf-life for chip-based systems is typically one month. If the lab has low sample volumes for a given month, then the excess gel adds to lab wastage.
• hidden cost: the chips themselves are good for only one year, at which point the manufacturer recommends they be thrown away.
• hidden cost: electrodes for running lab-on-a-chip systems must be cleaned daily with an ultrasonic device. This adds to labor costs.
• hidden cost: some systems require that sample aliquots be diluted with water, since their systems are sensitive to salts. This adds time to the labor process.
• hidden cost: gels mixed with dye for chip loading must be used by the end of each day, or thrown out. The excess waste from each day is an additional cost burden to the lab.

By comparison, the AdvanCE™ FS Nucleic Acids Analyzer was designed to reduce the costs of NGS fragment analysis runs, and bring automation benefits to lab workflow. By streamlining the analysis in a variety of ways, the AdvanCE™ Nucleic Acids Analyzer significantly reduces sample handling.

Combined with lower cost per sample to begin with, the overall price tag for executing runs with the AdvanCE™ FS Nucleic Acids Analyzer could be as much as 75% lower than chip-based methods.

The following factors allow the AdvanCE™ FS Nucleic Acids Analyzer to reduce analysis costs:

1. Simplified and automated sample handling capability.
2. No chips to prime or load with samples prior to use.
3. Easier instrument care and preparation.
4. Ability to handle 12 or 96 samples simultaneously.