I want to...

Automate Throughput	Decrease Labor Prep Time
Reduce Input gDNA	Stop Using Manual Slab Gels
Analzye Larger Fragments	Eliminate Clean Up Step
Increase Throughput	Reduce Time To Results
Eliminate Labeled Primers

I want to Decrease Labor Prep Time

Mutation detection by the conventional method is labor intensive, requiring the preparation of glass plates, plate assembly, preparation of gel and components, gel pouring, sample loading, gel plate disassembly and gel plate cleaning. In total over 2 hours of hands-on time is required per analysis.

The AdvanCE™ FS Nucleic Acids Analyzer eliminates these manual steps by utilizing a state-of-the-art analytical instrument which is capable of loading the gel, loading the samples and starting the electrophoresis automatically. By streamlining these steps, labor and preparation time is reduced by more than half compared to the conventional method.

In addition to the time gains from not having to prepare acrylamide gels, sample preparation has also been streamlined and poised for automated analysis on the AdvanCE™ FS Nucleic Acids Analyzer. The Mutation Detection Kit eliminates the clean up steps, shaving off additional time.

The following design features help decrease labor and preparation time for mutation detection on the AdvanCE™ FS Nucleic Acids Analyzer:

1. No glass plate assembly/disassembly or gel preparation requirements.
2. Elimination of Sephadex or ethanol precipitation clean-up steps.
3. Only three pipetting steps post heteroduplex formation are required to prepare samples for electrophoresis.